The description of the bacterium pseudomonas aeruginosa

Pseudomonas aeruginosa Scanning Electron Micrograph. From the Centers for Disease Control and Prevention CDC Description and significance Pseudomonas aeruginosa is a gram-negative, rod-shaped, asporogenous, and monoflagellated bacterium that has an incredible nutritional versatility. This, then, makes P. In all oligotropic aquatic ecosystems, which contain high-dissolved oxygen content but low plant nutrients throughout, P.

The description of the bacterium pseudomonas aeruginosa

Premature infants and neutropenic cancer patients Skin and soft tissue infections Hemorrhage and necrosis People with burns or wound infections It is the most common cause of infections of burn injuries and of the outer ear otitis externaand is the most frequent colonizer of medical devices e.

Pseudomonas can be spread by equipment that gets contaminated and is not properly cleaned or on the hands of healthcare workers. However, salicylic acid can inhibit pyocyanin production.

Cystic fibrosis patients are also predisposed to P.

The description of the bacterium pseudomonas aeruginosa

Since these bacteria like moist environments, such as hot tubs and swimming pools, they can cause skin rash or swimmer's ear. The organism is also associated with the skin lesion ecthyma gangrenosum. Toxins[ edit ] P. Without elongation factor 2, eukaryotic cells cannot synthesize proteins and necrotise.

The release of intracellular contents induces an immunologic response in immunocompetent patients. Increasingly, it is becoming recognized that the iron-acquiring siderophorepyoverdinealso functions as a toxin by removing iron from mitochondriainflicting damage on this organelle.

These pigments are involved in quorum sensingvirulenceand iron acquisition. Two operons are involved in phenazine biosynthesis: Three key genes, phzH, phzM, and phzS convert phenazinecarboxylic acid to the phenazines mentioned above. Though phenazine biosynthesis is well studied, questions remain as to the final structure of the brown phenazine pyomelanin.

When pyocyanin biosynthesis is inhibited, a decrease in P. Triggers[ edit ] With low phosphate levels, P. The extracellular accumulation of these molecules signals to bacteria to alter gene expression and coordinate behavior.

Another form of gene regulation that allows the bacteria to rapidly adapt to surrounding changes is through environmental signaling. Recent studies have discovered anaerobiosis can significantly impact the major regulatory circuit of QS.

This important link between QS and anaerobiosis has a significant impact on production of virulence factors of this organism. They often cannot be treated effectively with traditional antibiotic therapy. Biofilms seem to protect these bacteria from adverse environmental factors.

Researchers consider it important to learn more about the molecular mechanisms that cause the switch from planktonic growth to a biofilm phenotype and about the role of QS in treatment-resistant bacteria such as P.

This should contribute to better clinical management of chronically infected patients, and should lead to the development of new drugs.

One of the main gene operons responsible for the initiation and maintaining the biofilm is the PSL operon. It is also responsible for the sequestering of the extracellular polymeric substance matrix. This matrix is composed of nucleic acids, amino acids, carbohydrates, and various ions.

This matrix is one of the main resistance mechanisms in the biofilms of P.Pseudomonas infections are caused by a free-living bacterium from the genus Pseudomonas. They favor moist areas and are widely found in soil and water. Only a few of the many species cause disease.

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A detailed and testable scenario for the evolutionary origin of the bacterial flagellum. Pseudomonas Infections Definition A pseudomonas infection is caused by a bacterium, Pseudomonas aeruginosa, and may affect any part of the body.

In most cases, however, pseudomonas infections strike only persons who are very ill, usually hospitalized. Description P. aeruginosa is a rod-shaped organism that can be found in soil, water, plants, and.

Pseudomonas is also a common cause of postoperative infection in radial keratotomy surgery patients. The organism is also associated with the skin lesion ecthyma gangrenosum.

P. aeruginosa is frequently associated with osteomyelitis involving puncture wounds of the foot, believed to result from direct inoculation with P.

aeruginosa via the foam padding found in tennis shoes, with diabetic patients at a . Cetrimide agar is a type of agar used for the selective isolation of the gram-negative bacterium, Pseudomonas aeruginosa.

As the name suggests, it contains cetrimide, which is the selective agent against alternate microbial flora. Cetrimide also enhances the production of Pseudomonas pigments such as pyocyanin and fluorescein, which .

The Normal Bacterial Flora of Humans